Global Difficult-to-Express Proteins Market Size study, By Protein (Proteases, Kinases, Membrane Proteins, Others), By Technology (Cell-free Protein Synthesis, Prokaryotic Expression Systems, SUMO Fusion System, Gene Fusion Systems, Others), By Application (Drug Discovery, Protein Purification, Protein Therapeutics, Disease Diagnostics and Monitoring, Others), and Regional Forecasts 2022-2028

BIZ4983218
200 Pages
June 2022
Diagnostic and Biotech

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Global Difficult-to-Express Proteins Market is valued approximately USD XX million in 2021 and is anticipated to grow with a healthy growth rate of more than XX % over the forecast period 2022-2028. The Difficult-to-Express Proteins can be defined as proteins that cannot be easily synthesized in conventional in vivo protein production platforms. These proteins do not emerge in fully soluble, well-folded, and active form in a heterologous expression system due to their inherent properties. Proteins such as proteases, kinases, membrane proteins are considered as difficult to express proteins. The growing prevalence of chronic diseases and increasing end use applications of difficult-to-express proteins as well as recent clinical trials towards high proteins are accelerating the global market demand. For instance, according to World Health Organization (WHO) estimate – as of 2019, globally around 17.9 million people succumbs to cardiovascular diseases (CVDs), witnessing for 32% of all global deaths. Further, 85% of death were caused by heart attack and stroke. Moreover, in October 2021, Germany based Eleva, a leading manufacturer of superior biologics announced clinical development of Difficult-To-Express high-potential proteins. The company would produce complex proteins for future therapies, such as 2nd generation oncological therapeutics, and virus-like-particles (VLP) for vaccine development. Also, growing investment towards healthcare research and rising healthcare sector in emerging economics are anticipated to act as a catalyzing factor for the market demand during the forecast period. However, a high cost associated with these proteins impede the growth of the market over the forecast period of 2022-2028.

The key regions considered for the global Difficult-to-Express Proteins Market study include Asia Pacific, North America, Europe, Latin America, and the Rest of the World. North America is the leading region across the world in terms of market share owing to the growing spending on healthcare research activities and presence of leading pharma players in the region. Whereas, Asia Pacific is anticipated to exhibit a significant growth rate over the forecast period 2022-2028. Factors such as the thriving growth of clinical research organizations and increasing penetration of leading market players in the region, would create lucrative growth prospects for the global Difficult-to-Express Proteins Market across the Asia Pacific region.

Major market players included in this report are:

R&D Systems

Enzo Life Sciences

Sino Biological

Thermo Fisher Scientific

StressMarq Biosciences

LifeSensors Inc.

Lucigen

Batavia Biosciences Inc.

WuXi Biologics

Selexis SA

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Protein

Proteases

Kinases

Membrane Proteins

Others

By Technology

Cell-free Protein Synthesis

Prokaryotic Expression Systems

SUMO Fusion System

Gene Fusion Systems

Others

By Application

Drug Discovery

Protein Purification

Protein Therapeutics

Disease Diagnostics and Monitoring

Others

By Region:

North America

U.S.

Canada

Europe

Germany

France

Spain

Italy

ROE

Asia Pacific

China

India

Japan

Australia

South Korea

RoAPAC

Latin America

Brazil

Mexico

Rest of the World

Furthermore, years considered for the study are as follows:

Historical year – 2018, 2019, 2020

Base year – 2021

Forecast period – 2022 to 2028

Target Audience of the Global Difficult-to-Express Proteins Market in Market Study:

Key Consulting Companies & Advisors

Large, medium-sized, and small enterprises

Venture capitalists

Value-Added Resellers (VARs)

Third-party knowledge providers

Investment bankers

Investors

Chapter 1. Executive Summary

1.1. Market Snapshot

1.2. Global & Segmental Market Estimates & Forecasts, 2020-2028 (USD Million)

1.2.1. Global Difficult-to-Express Proteins Market, by Region, 2020-2028 (USD Million)

1.2.2. Global Difficult-to-Express Proteins Market, by Protein, 2020-2028 (USD Million)

1.2.3. Global Difficult-to-Express Proteins Market, by Technology, 2020-2028 (USD Million)

1.2.4. Global Difficult-to-Express Proteins Market, by Application, 2020-2028 (USD Million)

1.3. Key Trends

1.4. Estimation Methodology

1.5. Research Assumption

Chapter 2. Global Difficult-to-Express Proteins Market Definition and Scope

2.1. Objective of the Study

2.2. Market Definition & Scope

2.2.1. Scope of the Study

2.2.2. Industry Evolution

2.3. Years Considered for the Study

2.4. Currency Conversion Rates

Chapter 3. Global Difficult-to-Express Proteins Market Dynamics

3.1. Difficult-to-Express Proteins Market Impact Analysis (2020-2028)

3.1.1. Market Drivers

3.1.1.1. Growing prevalence of chronic diseases.

3.1.1.2. Increasing end use applications of difficult-to-express proteins.

3.1.1.3. Recent clinical trials towards high proteins.

3.1.2. Market Challenges

3.1.2.1. High cost associated with these proteins.

3.1.3. Market Opportunities

3.1.3.1. Growing investment towards healthcare research.

3.1.3.2. Rising healthcare sector in emerging economics.

Chapter 4. Global Difficult-to-Express Proteins Market Industry Analysis

4.1. Porter’s 5 Force Model

4.1.1. Bargaining Power of Suppliers

4.1.2. Bargaining Power of Buyers

4.1.3. Threat of New Entrants

4.1.4. Threat of Substitutes

4.1.5. Competitive Rivalry

4.1.6. Futuristic Approach to Porter’s 5 Force Model (2018-2028)

4.2. PEST Analysis

4.2.1. Political

4.2.2. Economical

4.2.3. Social

4.2.4. Technological

4.3. Investment Adoption Model

4.4. Analyst Recommendation & Conclusion

4.5. Top investment opportunity

4.6. Top winning strategies

Chapter 5. Risk Assessment: COVID-19 Impact

5.1.1. Assessment of the overall impact of COVID-19 on the industry

5.1.2. Pre COVID-19 and post COVID-19 Market scenario

Chapter 6. Global Difficult-to-Express Proteins Market, by Protein

6.1. Market Snapshot

6.2. Global Difficult-to-Express Proteins Market by Protein, Performance - Potential Analysis

6.3. Global Difficult-to-Express Proteins Market Estimates & Forecasts by Protein 2018-2028 (USD Million)

6.4. Difficult-to-Express Proteins Market, Sub Segment Analysis

6.4.1. Proteases

6.4.2. Kinases

6.4.3. Membrane Proteins

6.4.4. Others

Chapter 7. Global Difficult-to-Express Proteins Market, by Technology

7.1. Market Snapshot

7.2. Global Difficult-to-Express Proteins Market by Technology, Performance - Potential Analysis

7.3. Global Difficult-to-Express Proteins Market Estimates & Forecasts by Technology 2018-2028 (USD Million)

7.4. Difficult-to-Express Proteins Market, Sub Segment Analysis

7.4.1. Cell-free Protein Synthesis

7.4.2. Prokaryotic Expression Systems

7.4.3. SUMO Fusion System

7.4.4. Gene Fusion Systems

7.4.5. Others

Chapter 8. Global Difficult-to-Express Proteins Market, by Application

8.1. Market Snapshot

8.2. Global Difficult-to-Express Proteins Market by Application, Performance - Potential Analysis

8.3. Global Difficult-to-Express Proteins Market Estimates & Forecasts by Application 2018-2028 (USD Million)

8.4. Difficult-to-Express Proteins Market, Sub Segment Analysis

8.4.1. Drug Discovery

8.4.2. Protein Purification

8.4.3. Protein Therapeutics

8.4.4. Disease Diagnostics and Monitoring

8.4.5. Others

Chapter 9. Global Difficult-to-Express Proteins Market, Regional Analysis

9.1. Difficult-to-Express Proteins Market, Regional Market Snapshot

9.2. North America Difficult-to-Express Proteins Market

9.2.1. U.S. Difficult-to-Express Proteins Market

9.2.1.1. Protein estimates & forecasts, 2018-2028

9.2.1.2. Technology estimates & forecasts, 2018-2028

9.2.1.3. Application estimates & forecasts, 2018-2028

9.2.2. Canada Difficult-to-Express Proteins Market

9.3. Europe Difficult-to-Express Proteins Market Snapshot

9.3.1. U.K. Difficult-to-Express Proteins Market

9.3.2. Germany Difficult-to-Express Proteins Market

9.3.3. France Difficult-to-Express Proteins Market

9.3.4. Spain Difficult-to-Express Proteins Market

9.3.5. Italy Difficult-to-Express Proteins Market

9.3.6. Rest of Europe Difficult-to-Express Proteins Market

9.4. Asia-Pacific Difficult-to-Express Proteins Market Snapshot

9.4.1. China Difficult-to-Express Proteins Market

9.4.2. India Difficult-to-Express Proteins Market

9.4.3. Japan Difficult-to-Express Proteins Market

9.4.4. Australia Difficult-to-Express Proteins Market

9.4.5. South Korea Difficult-to-Express Proteins Market

9.4.6. Rest of Asia Pacific Difficult-to-Express Proteins Market

9.5. Latin America Difficult-to-Express Proteins Market Snapshot

9.5.1. Brazil Difficult-to-Express Proteins Market

9.5.2. Mexico Difficult-to-Express Proteins Market

9.6. Rest of The World Difficult-to-Express Proteins Market

Chapter 10. Competitive Intelligence

10.1. Top Market Strategies

10.2. Company Profiles

10.2.1. R&D Systems

10.2.1.1. Key Information

10.2.1.2. Overview

10.2.1.3. Financial (Subject to Data Availability)

10.2.1.4. Product Summary

10.2.1.5. Recent Developments

10.2.2. Enzo Life Sciences

10.2.3. Sino Biological

10.2.4. Thermo Fisher Scientific

10.2.5. StressMarq Biosciences

10.2.6. LifeSensors Inc.

10.2.7. Lucigen

10.2.8. Batavia Biosciences Inc.

10.2.9. WuXi Biologics

10.2.10. Selexis SA

Chapter 11. Research Process

11.1. Research Process

11.1.1. Data Mining

11.1.2. Analysis

11.1.3. Market Estimation

11.1.4. Validation

11.1.5. Publishing

11.2. Research Attributes

11.3. Research Assumption

List of Tables

TABLE 1. Global Difficult-to-Express Proteins Market, report scope

TABLE 2. Global Difficult-to-Express Proteins Market estimates & forecasts by Region 2018-2028 (USD Million)

TABLE 3. Global Difficult-to-Express Proteins Market estimates & forecasts by Protein 2018-2028 (USD Million)

TABLE 4. Global Difficult-to-Express Proteins Market estimates & forecasts by Technology 2018-2028 (USD Million)

TABLE 5. Global Difficult-to-Express Proteins Market estimates & forecasts by Application 2018-2028 (USD Million)

TABLE 6. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)

TABLE 7. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)

TABLE 8. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)

TABLE 9. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)

TABLE 10. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)

TABLE 11. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)

TABLE 12. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)

TABLE 13. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)

TABLE 14. Global Difficult-to-Express Proteins Market by segment, estimates & forecasts, 2018-2028 (USD Million)

TABLE 15. Global Difficult-to-Express Proteins Market by region, estimates & forecasts, 2018-2028 (USD Million)

TABLE 16. U.S. Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 17. U.S. Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 18. U.S. Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 19. Canada Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 20. Canada Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 21. Canada Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 22. UK Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 23. UK Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 24. UK Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 25. Germany Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 26. Germany Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 27. Germany Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 28. RoE Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 29. RoE Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 30. RoE Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 31. China Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 32. China Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 33. China Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 34. India Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 35. India Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 36. India Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 37. Japan Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 38. Japan Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 39. Japan Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 40. RoAPAC Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 41. RoAPAC Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 42. RoAPAC Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 43. Brazil Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 44. Brazil Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 45. Brazil Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 46. Mexico Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 47. Mexico Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 48. Mexico Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 49. RoLA Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 50. RoLA Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 51. RoLA Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 52. Row Difficult-to-Express Proteins Market estimates & forecasts, 2018-2028 (USD Million)

TABLE 53. Row Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 54. Row Difficult-to-Express Proteins Market estimates & forecasts by segment 2018-2028 (USD Million)

TABLE 55. List of secondary sources, used in the study of global Difficult-to-Express Proteins Market

TABLE 56. List of primary sources, used in the study of global Difficult-to-Express Proteins Market

TABLE 57. Years considered for the study

TABLE 58. Exchange rates considered

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