Global Active Pharmaceutical Ingredients (API) Market 2021-2028 by Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Region: Trend Forecast and Growth Opportunity
- GRA4881394
- 254 Pages
- February 2022
- Healthcare
Highlighted with 146 tables and 104 figures, this 254-page report “Global Active Pharmaceutical Ingredients (API) Market 2021-2028 by Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Region: Trend Forecast and Growth Opportunity” is based on a comprehensive research of the entire global active pharmaceutical ingredients market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2018-2021 and provides forecast from 2022 till 2028 with 2021 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)
In-depth qualitative analyses include identification and investigation of the following aspects:
• Market Structure
• Growth Drivers
• Restraints and Challenges
• Emerging Product Trends & Market Opportunities
• Porter’s Fiver Forces
The trend and outlook of global market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19. The balanced (most likely) projection is used to quantify global active pharmaceutical ingredients market in every aspect of the classification from perspectives of Synthesis, Manufacturing Process, Therapeutic Application, Drug Type, and Region.
Based on Synthesis, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
Synthetic API
• Branded Synthetic API
• Generic Synthetic API
Biotech API by Drug Type:
• Monoclonal Antibodies
• Recombinant Proteins
• Vaccines
• Other Biotech APIs
Biotech API by Customer Base:
• Innovative Biologic API
• Generic Biosimilar API
Biotech API by Expression Technology:
• Mammalian Expression
• Microbial Expression
• Yeast Expression
• Insect Expression
• Other Expression Technologies
HPAPI
• Branded HPAPI
• Generic HPAPI
Based on Manufacturing Process, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
Captive Manufacturing
• Branded Captive API
• Generic Captive API
Merchant Manufacturing by Drug Type:
• Branded Merchant API
• Generic Merchant API
Merchant Manufacturing by Drug Synthesis:
• Merchant Synthetic API
• Merchant Biotech API
By Therapeutic Application, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
• Infectious Diseases
• Oncology
• Ophthalmology
• Cardiovascular Disorders
• Central Nervous System
• Pulmonary Disorders
• Orthopedics
• Other Applications
By Drug Type, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.
• Branded Prescription Drugs
• Generic Prescription Drugs
• OTC Drugs
Geographically, the following regions together with the listed national/local markets are fully investigated:
• North America (U.S., Canada, and Mexico)
• Europe (Germany, UK, France, Spain, Italy, Russia, Rest of Europe; Rest of Europe is further segmented into Netherlands, Switzerland, Poland, Sweden, Belgium, Austria, Ireland, Norway, Denmark, and Finland)
• APAC (Japan, China, South Korea, Australia, India, and Rest of APAC; Rest of APAC is further segmented into Indonesia, Malaysia, New Zealand, Singapore, Thailand, and Vietnam)
• South America (Brazil, Chile, Argentina, Rest of South America)
• MEA (UAE, Saudi Arabia, South Africa, Other Nations)
For each aforementioned region and country, detailed analysis and data for annual revenue ($ bn) are available for 2018-2028. The breakdown of all regional markets by country and split of key national markets by Synthesis, Manufacturing Process, and Therapeutic Application, over the forecast years are also included.
The report also covers current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.
Selected Key Players:
AbbVie Inc.
Astrazeneca
Aurobindo Pharma Ltd.
BASF
Bayer AG
Boehringer Ingelheim
Catalent Inc.
Dr. Reddy's Laboratories
F. Hoffmann-La Roche
GlaxoSmithKline plc
Lonza Group
Lupin Limited
Merck & Co., Inc.
Mylan NV
Novartis International AG
Pfizer Inc.
Sanofi
Sun Pharmaceutical Industries Ltd.
Teva Pharmaceutical Industries Ltd.
Thermo Fisher Scientific
(Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)
1.1 Industry Definition and Research Scope 12
1.1.1 Industry Definition 12
1.1.2 Research Scope 13
1.2 Research Methodology 16
1.2.1 Overview of Market Research Methodology 16
1.2.2 Market Assumption 17
1.2.3 Secondary Data 17
1.2.4 Primary Data 17
1.2.5 Data Filtration and Model Design 18
1.2.6 Market Size/Share Estimation 19
1.2.7 Research Limitations 20
1.3 Executive Summary 21
2 Market Overview and Dynamics 23
2.1 Market Size and Forecast 23
2.1.1 Impact of COVID-19 on World Economy 24
2.1.2 Impact of COVID-19 on the Market 26
2.2 Major Growth Drivers 33
2.3 Market Restraints and Challenges 41
2.4 Emerging Opportunities and Market Trends 44
2.5 Porter’s Fiver Forces Analysis 48
3 Segmentation of Global Market by Synthesis 52
3.1 Market Overview by Synthesis 52
3.2 Synthetic API 54
3.2.1 Branded Synthetic API 55
3.2.2 Generic Synthetic API 56
3.3 Biotech API 57
3.3.1 Biotech API by Drug Type 58
3.3.1.1 Monoclonal Antibodies 59
3.3.1.2 Recombinant Proteins 60
3.3.1.3 Vaccines 61
3.3.1.4 Other Biotech APIs 62
3.3.2 Biotech API by Category 63
3.3.2.1 Innovative Biologic API 64
3.3.2.2 Generic Biosimilar API 65
3.3.3 Biotech API by Expression Technology 66
3.3.3.1 Mammalian Expression 67
3.3.3.2 Microbial Expression 68
3.3.3.3 Yeast Expression 69
3.3.3.4 Insect Expression 70
3.3.3.5 Other Expression Technologies 71
3.4 HPAPI 72
3.4.1 Branded HPAPI 73
3.4.2 Generic HPAPI 74
4 Segmentation of Global Market by Manufacturing Process 75
4.1 Market Overview by Manufacturing Process 75
4.2 Captive Manufacturing 77
4.2.1 Branded Captive API 78
4.2.2 Generic Captive API 79
4.3 Merchant Manufacturing 80
4.3.1 Merchant Manufacturing by Drug Type 81
4.3.1.1 Branded Merchant API 82
4.3.1.2 Generic Merchant API 83
4.3.2 Merchant Manufacturing by Drug Synthesis 84
4.3.2.1 Merchant Synthetic API 85
4.3.2.2 Merchant Biotech API 86
5 Segmentation of Global Market by Therapeutic Application 87
5.1 Market Overview by Therapeutic Application 87
5.2 Infectious Diseases 89
5.3 Oncology 90
5.4 Ophthalmology 91
5.5 Cardiovascular Disorders 92
5.6 Central Nervous System 93
5.7 Pulmonary Disorders 94
5.8 Orthopedics 95
5.9 Other Applications 96
6 Segmentation of Global Market by Drug Type 97
6.1 Market Overview by Drug Type 97
6.2 Branded Prescription Drugs 99
6.3 Generic Prescription Drugs 100
6.4 OTC Drugs 101
7 Segmentation of Global Market by Region 102
7.1 Geographic Market Overview 2021-2028 102
7.2 North America Market 2021-2028 by Country 107
7.2.1 Overview of North America Market 107
7.2.2 U.S. 110
7.2.3 Canada 121
7.2.4 Mexico 123
7.3 European Market 2021-2028 by Country 125
7.3.1 Overview of European Market 125
7.3.2 UK 128
7.3.3 France 130
7.3.4 Germany 132
7.3.5 Spain 134
7.3.6 Italy 136
7.3.7 Russia 138
7.3.8 Rest of European Market 140
7.4 Asia-Pacific Market 2021-2028 by Country 142
7.4.1 Overview of Asia-Pacific Market 142
7.4.2 China 145
7.4.3 Japan 147
7.4.4 India 150
7.4.5 Australia 152
7.4.6 South Korea 154
7.4.7 Rest of APAC Region 156
7.5 South America Market 2021-2028 by Country 158
7.5.1 Argentina 161
7.5.2 Brazil 163
7.5.3 Chile 165
7.5.4 Rest of South America Market 167
7.6 Rest of World Market 2021-2028 by Country 168
7.6.1 UAE 171
7.6.2 Saudi Arabia 173
7.6.3 South Africa 175
7.6.4 Other National Markets 177
8 Competitive Landscape 178
8.1 Overview of Key Vendors 178
8.2 New Product Launch, Partnership, Investment, and M&A 181
8.3 Company Profiles 182
AbbVie Inc. 182
Astrazeneca 184
Aurobindo Pharma Ltd. 189
BASF 192
Bayer AG 195
Boehringer Ingelheim 199
Catalent Inc. 204
Dr. Reddy's Laboratories 207
F. Hoffmann-La Roche 209
GlaxoSmithKline plc 211
Lonza Group 216
Lupin Limited 221
Merck & Co., Inc. 224
Mylan NV 227
Novartis International AG 230
Pfizer Inc. 233
Sanofi 238
Sun Pharmaceutical Industries Ltd. 241
Teva Pharmaceutical Industries Ltd. 244
Thermo Fisher Scientific 246
9 Investing in Global Market: Risk Assessment and Management 248
9.1 Risk Evaluation of Global Market 248
9.2 Critical Success Factors (CSFs) 251
Related Reports and Products 254
Table 1. Snapshot of Global Active Pharmaceutical Ingredients (API) Market in Balanced Perspective, 2021-2028 22
Table 2. World Economic Outlook, 2021-2031 25
Table 3. World Top 10 Pharmaceutical Companies Based on Projected R&D Spending in 2026, $ bn 40
Table 4. Main Product Trends and Market Opportunities in Global Active Pharmaceutical Ingredients (API) Market 44
Table 5. Global Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 52
Table 6. Global Active Pharmaceutical Ingredients (API) Market: Synthetic API by Drug Type, 2018-2028, $ bn 54
Table 7. Global Active Pharmaceutical Ingredients (API) Market: Biotech API by Drug Type, 2018-2028, $ bn 58
Table 8. Global Active Pharmaceutical Ingredients (API) Market: Biotech API by Category, 2018-2028, $ bn 63
Table 9. Global Active Pharmaceutical Ingredients (API) Market: Biotech API by Expression Technology, 2018-2028, $ bn 66
Table 10. Global Active Pharmaceutical Ingredients (API) Market: HPAPI by Drug Type, 2018-2028, $ bn 72
Table 11. Global Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 75
Table 12. Global Active Pharmaceutical Ingredients (API) Market: Captive Manufacturing by Drug Type, 2018-2028, $ bn 77
Table 13. Global Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Type, 2018-2028, $ bn 81
Table 14. Global Active Pharmaceutical Ingredients (API) Market: Merchant Manufacturing by Drug Synthesis, 2018-2028, $ bn 84
Table 15. Global Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 87
Table 16. Global Active Pharmaceutical Ingredients (API) Market by Drug Type, 2018-2028, $ bn 97
Table 17. Global Active Pharmaceutical Ingredients (API) Market by Region, 2018-2028, $ bn 103
Table 18. World Health Spending by Region, $ bn, 2013-2020 105
Table 19. Leading National Active Pharmaceutical Ingredients (API) Market, 2021 and 2028, $ bn 106
Table 20. North America Active Pharmaceutical Ingredients (API) Market by Country, 2018-2028, $ bn 109
Table 21. U.S. Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 112
Table 22. U.S. Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 112
Table 23. U.S. Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 112
Table 24. Top 15 Countries Supplying API for Medicines Consumed in the US, 2019, % based on Dollar Value 115
Table 25. Canada Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 122
Table 26. Canada Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 122
Table 27. Canada Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 122
Table 28. Mexico Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 124
Table 29. Mexico Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 124
Table 30. Mexico Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 124
Table 31. Europe Active Pharmaceutical Ingredients (API) Market by Country, 2018-2028, $ bn 127
Table 32. UK Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 129
Table 33. UK Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 129
Table 34. UK Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 129
Table 35. France Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 131
Table 36. France Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 131
Table 37. France Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 131
Table 38. Germany Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 133
Table 39. Germany Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 133
Table 40. Germany Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 133
Table 41. Spain Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 135
Table 42. Spain Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 135
Table 43. Spain Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 135
Table 44. Italy Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 137
Table 45. Italy Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 137
Table 46. Italy Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 137
Table 47. Russia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 139
Table 48. Russia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 139
Table 49. Russia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 139
Table 50. Active Pharmaceutical Ingredients (API) Market in Rest of Europe by Country, 2018-2028, $ bn 141
Table 51. APAC Active Pharmaceutical Ingredients (API) Market by Country, 2018-2028, $ bn 144
Table 52. China Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 146
Table 53. China Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 146
Table 54. China Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 146
Table 55. Japan Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 149
Table 56. Japan Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 149
Table 57. Japan Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 149
Table 58. India Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 151
Table 59. India Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 151
Table 60. India Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 151
Table 61. Australia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 153
Table 62. Australia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 153
Table 63. Australia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 153
Table 64. South Korea Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 155
Table 65. South Korea Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 155
Table 66. South Korea Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 155
Table 67. Active Pharmaceutical Ingredients (API) Market in Rest of APAC by Country, 2018-2028, $ bn 157
Table 68. South America Active Pharmaceutical Ingredients (API) Market by Country, 2018-2028, $ bn 160
Table 69. Argentina Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 162
Table 70. Argentina Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 162
Table 71. Argentina Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 162
Table 72. Brazil Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 164
Table 73. Brazil Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 164
Table 74. Brazil Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 164
Table 75. Chile Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 166
Table 76. Chile Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 166
Table 77. Chile Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 166
Table 78. RoW Active Pharmaceutical Ingredients (API) Market by Country, 2018-2028, $ bn 170
Table 79. UAE Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 172
Table 80. UAE Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 172
Table 81. UAE Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 172
Table 82. Saudi Arabia Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 174
Table 83. Saudi Arabia Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 174
Table 84. Saudi Arabia Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 174
Table 85. South Africa Active Pharmaceutical Ingredients (API) Market by Synthesis, 2018-2028, $ bn 176
Table 86. South Africa Active Pharmaceutical Ingredients (API) Market by Manufacturing Process, 2018-2028, $ bn 176
Table 87. South Africa Active Pharmaceutical Ingredients (API) Market by Therapeutic Application, 2018-2028, $ bn 176
Table 88. AbbVie Inc.: Company Snapshot 182
Table 89. AbbVie Inc.: Product Portfolio 182
Table 90. AbbVie Inc.: Revenue, 2018-2020, $ bn 183
Table 91. Astrazeneca: Company Snapshot 184
Table 92. Astrazeneca: Revenue, 2018-2020, $ bn 185
Table 93. Aurobindo Pharma Ltd.: Company Snapshot 189
Table 94. Aurobindo Pharma Ltd.: Product Portfolio 190
Table 95. BASF: Company Snapshot 192
Table 96. BASF: Business Segmentation 193
Table 97. BASF: Revenue by Region 193
Table 98. Bayer AG: Company Snapshot 195
Table 99. Bayer AG: Business Segmentation 196
Table 100. Bayer AG: Revenue, 2018-2020, € bn 196
Table 101. Boehringer Ingelheim: Company Snapshot 199
Table 102. Boehringer Ingelheim: Business Segmentation in 2019 200
Table 103. Boehringer Ingelheim: Product Portfolio 200
Table 104. Boehringer Ingelheim: Revenue, 2018-2020, EUR billion 201
Table 105. Boehringer Ingelheim: Revenue by Region in 2019 201
Table 106. Catalent Inc.: Company Snapshot 204
Table 107. Catalent Inc.: Business Segmentation in 2018 205
Table 108. Catalent Inc.: Product Portfolio 205
Table 109. Catalent Inc.: Revenue, 2018-2020, $ million 206
Table 110. Catalent Inc.: Revenue by Region in 2018 206
Table 111. Dr. Reddy's Laboratories: Company Snapshot 207
Table 112. Dr. Reddy's Laboratories: Business Segmentation 207
Table 113. Dr. Reddy's Laboratories: Revenue, 2019-2021, $ bn 208
Table 114. F. Hoffmann-La Roche: Company Snapshot 209
Table 115. F. Hoffmann-La Roche: Business Segmentation 210
Table 116. GlaxoSmithKline: Company Snapshot 211
Table 117. GlaxoSmithKline: Business Segmentation 212
Table 118. GlaxoSmithKline: Product Portfolio 213
Table 119. GlaxoSmithKline: Revenue, 2018-2020, $ bn 214
Table 120. Lonza Group: Company Snapshot 216
Table 121. Lonza Group: Business Segmentation in 2018 217
Table 122. Lonza Group: Product Portfolio 217
Table 123. Lonza Group: Revenue by Region in 2018 218
Table 124. Lupin Limited: Company Snapshot 221
Table 125. Lupin Limited: Business Segmentation 221
Table 126. Merck & Co., Inc.: Company Snapshot 224
Table 127. Merck & Co., Inc.: Business Segmentation 224
Table 128. Merck & Co., Inc.: Revenue, 2018-2020, $ bn 225
Table 129. Mylan NV: Company Snapshot 227
Table 130. Mylan NV: Revenue, 2017-2019, $ bn 228
Table 131. Novartis International AG: Company Snapshot 230
Table 132. Novartis International AG: Business Segmentation 230
Table 133. Novartis International AG: Revenue, 2017-2019, $ bn 231
Table 134. Pfizer Inc.: Company Snapshot 233
Table 135. Pfizer Inc.: Business Segmentation 234
Table 136. Pfizer Inc.: Product Portfolio 235
Table 137. Pfizer Inc.: Revenue, 2018-2020, $ bn 235
Table 138. Sanofi: Company Snapshot 238
Table 139. Sanofi: Business Segmentation 238
Table 140. Sanofi: Revenue, 2018-2020, $ bn 239
Table 141. Sun Pharmaceutical Industries Limited: Company Snapshot 241
Table 142. Teva Pharmaceutical Industries Ltd.: Company Snapshot 244
Table 143. Teva Pharmaceutical Industries Ltd.: Business Segmentation 245
Table 144. Thermo Fisher Scientific: Company Snapshot 246
Table 145. Risk Evaluation for Investing in Global Market, 2021-2028 249
Table 146. Critical Success Factors and Key Takeaways 252
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