Global CIS Insulin Market Report 2019 - market Size, Share, Price, Trend and Forecast
- PRO3190157
- 102 Pages
- June 2019
- Medical Devices
Global CIS Insulin Market Report 2019 - Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global CIS Insulin industry. The key insights of the report:
1.The report provides key statistics on the market status of the CIS Insulin manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.
2.The report provides a basic overview of the industry including its definition, applications and manufacturing technology.
3.The report presents the company profile, product specifications, capacity, production value, and 2013-2018 market shares for key vendors.
4.The total market is further divided by company, by country, and by application/type for the competitive landscape analysis.
5.The report estimates 2019-2024 market development trends of CIS Insulin industry.
6.Analysis of upstream raw materials, downstream demand, and current market dynamics is also carried out
7.The report makes some important proposals for a new project of CIS Insulin Industry before evaluating its feasibility.
There are 4 key segments covered in this report: competitor segment, product type segment, end use/application segment and geography segment.
For competitor segment, the report includes global key players of CIS Insulin as well as some small players. At least 9 companies are included:
* Eli Lilly
* Novo Nordisk
* Takeda Pharmaceuticals
* Sanofi Aventis
* Nanjing Xinbai Pharmaceutical
* Oramed Pharmaceuticals
For complete companies list, please ask for sample pages.
The information for each competitor includes:
* Company Profile
* Main Business Information
* SWOT Analysis
* Sales, Revenue, Price and Gross Margin
* Market Share
For product type segment, this report listed main product type of CIS Insulin market
* Product Type I
* Product Type II
* Product Type III
For end use/application segment, this report focuses on the status and outlook for key applications. End users sre also listed.
* Type I and Other Diabetes
* Type II Diabetes
For geography segment, regional supply, application-wise and type-wise demand, major players, price is presented from 2013 to 2023. This report covers following regions:
* North America
* South America
* Asia & Pacific
* Europe
* MEA (Middle East and Africa)
The key countries in each region are taken into consideration as well, such as United States, China, Japan, India, Korea, ASEAN, Germany, France, UK, Italy, Spain, CIS, and Brazil etc.
Reasons to Purchase this Report:
* Analyzing the outlook of the market with the recent trends and SWOT analysis
* Market dynamics scenario, along with growth opportunities of the market in the years to come
* Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and non-economic aspects
* Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
* Market value (USD Million) and volume (Units Million) data for each segment and sub-segment
* Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
* Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
* 1-year analyst support, along with the data support in excel format.
We also can offer customized report to fulfill special requirements of our clients. Regional and Countries report can be provided as well.
Chapter 1 Executive Summary
Chapter 2 Abbreviation and Acronyms
Chapter 3 Preface
3.1 Research Scope
3.2 Research Methodology
3.2.1 Primary Sources
3.2.2 Secondary Sources
3.2.3 Assumptions
Chapter 4 Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users
Chapter 5 Market Trend Analysis
5.1 Introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats
Chapter 6 Industry Chain Analysis
6.1 Upstream/Suppliers Analysis
6.2 CIS Insulin Analysis
6.2.1 Technology Analysis
6.2.2 Cost Analysis
6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users
Chapter 7 Latest Market Dynamics
7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics
Chapter 8 Trading Analysis
8.1 Export of CIS Insulin by Region
8.2 Import of CIS Insulin by Region
8.3 Balance of Trade
Chapter 9 Historical and Current CIS Insulin in North America (2013-2018)
9.1 CIS Insulin Supply
9.2 CIS Insulin Demand by End Use
9.3 Competition by Players/Suppliers
9.4 Type Segmentation and Price
9.5 Key Countries Analysis
9.5.1 US
9.5.2 Canada
9.5.3 Mexico
Chapter 10 Historical and Current CIS Insulin in South America (2013-2018)
10.1 CIS Insulin Supply
10.2 CIS Insulin Demand by End Use
10.3 Competition by Players/Suppliers
10.4 Type Segmentation and Price
10.5 Key Countries Analysis
10.5.1 Brazil
10.5.2 Argentina
10.5.3 Chile
10.5.4 Peru
Chapter 11 Historical and Current CIS Insulin in Asia & Pacific (2013-2018)
11.1 CIS Insulin Supply
11.2 CIS Insulin Demand by End Use
11.3 Competition by Players/Suppliers
11.4 Type Segmentation and Price
11.5 Key Countries Analysis
11.5.1 China
11.5.2 India
11.5.3 Japan
11.5.4 South Korea
11.5.5 ASEAN
11.5.6 Australia
Chapter 12 Historical and Current CIS Insulin in Europe (2013-2018)
12.1 CIS Insulin Supply
12.2 CIS Insulin Demand by End Use
12.3 Competition by Players/Suppliers
12.4 Type Segmentation and Price
12.5 Key Countries Analysis
12.5.1 Germany
12.5.2 France
12.5.3 UK
12.5.4 Italy
12.5.5 Spain
12.5.6 Belgium
12.5.7 Netherlands
12.5.8 Austria
12.5.9 Poland
12.5.10 Russia
Chapter 13 Historical and Current CIS Insulin in MEA (2013-2018)
13.1 CIS Insulin Supply
13.2 CIS Insulin Demand by End Use
13.3 Competition by Players/Suppliers
13.4 Type Segmentation and Price
13.5 Key Countries Analysis
13.5.1 Egypt
13.5.2 Iran
13.5.3 Israel
13.5.4 South Africa
13.5.5 GCC
13.5.6 Turkey
Chapter 14 Summary for Global CIS Insulin (2013-2018)
14.1 CIS Insulin Supply
14.2 CIS Insulin Demand by End Use
14.3 Competition by Players/Suppliers
14.4 Type Segmentation and Price
Chapter 15 Global CIS Insulin Forecast (2019-2023)
15.1 CIS Insulin Supply Forecast
15.2 CIS Insulin Demand Forecast
15.3 Competition by Players/Suppliers
15.4 Type Segmentation and Price Forecast
Chapter 16 Analysis of Global Key Vendors
16.1 Eli Lilly
16.1.1 Company Profile
16.1.2 Main Business and CIS Insulin Information
16.1.3 SWOT Analysis of Eli Lilly
16.1.4 Eli Lilly CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
16.2 Novo Nordisk
16.2.1 Company Profile
16.2.2 Main Business and CIS Insulin Information
16.2.3 SWOT Analysis of Novo Nordisk
16.2.4 Novo Nordisk CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
16.3 Takeda Pharmaceuticals
16.3.1 Company Profile
16.3.2 Main Business and CIS Insulin Information
16.3.3 SWOT Analysis of Takeda Pharmaceuticals
16.3.4 Takeda Pharmaceuticals CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
16.4 Sanofi Aventis
16.4.1 Company Profile
16.4.2 Main Business and CIS Insulin Information
16.4.3 SWOT Analysis of Sanofi Aventis
16.4.4 Sanofi Aventis CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
16.5 Nanjing Xinbai Pharmaceutical
16.5.1 Company Profile
16.5.2 Main Business and CIS Insulin Information
16.5.3 SWOT Analysis of Nanjing Xinbai Pharmaceutical
16.5.4 Nanjing Xinbai Pharmaceutical CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
16.6 Oramed Pharmaceuticals
16.6.1 Company Profile
16.6.2 Main Business and CIS Insulin Information
16.6.3 SWOT Analysis of Oramed Pharmaceuticals
16.6.4 Oramed Pharmaceuticals CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
16.7 Merck
16.7.1 Company Profile
16.7.2 Main Business and CIS Insulin Information
16.7.3 SWOT Analysis of Merck
16.7.4 Merck CIS Insulin Sales, Revenue, Price and Gross Margin (2014-2019)
......
......
Tables and Figures
Table Abbreviation and Acronyms List
Table Research Scope of CIS Insulin Report
Table Primary Sources of CIS Insulin Report
Table Secondary Sources of CIS Insulin Report
Table Major Assumptions of CIS Insulin Report
Figure CIS Insulin Picture
Table CIS Insulin Classification
Table CIS Insulin Applications List
Table Drivers of CIS Insulin Market
Table Restraints of CIS Insulin Market
Table Opportunities of CIS Insulin Market
Table Threats of CIS Insulin Market
Table Raw Materials Suppliers List
Table Different Production Methods of CIS Insulin
Table Cost Structure Analysis of CIS Insulin
Table Key End Users List
Table Latest News of CIS Insulin Market
Table Merger and Acquisition List
Table Planned/Future Project of CIS Insulin Market
Table Policy of CIS Insulin Market
Table 2014-2024 Regional Export of CIS Insulin
Table 2014-2024 Regional Import of CIS Insulin
Table 2014-2024 Regional Trade Balance
Figure 2014-2024 Regional Trade Balance
Table 2014-2024 North America CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Figure 2014-2024 North America CIS Insulin Market Size (M USD) and CAGR
Figure 2014-2024 North America CIS Insulin Market Volume (Tons) and CAGR
Table 2014-2024 North America CIS Insulin Demand (Tons) List by Application
Table 2014-2019 North America CIS Insulin Key Players Sales (Tons) List
Table 2014-2019 North America CIS Insulin Key Players Market Share List
Table 2014-2024 North America CIS Insulin Demand (Tons) List by Type
Table 2014-2019 North America CIS Insulin Price (USD/Ton) List by Type
Table 2014-2024 US CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 US CIS Insulin Import & Export (Tons) List
Table 2014-2024 Canada CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Canada CIS Insulin Import & Export (Tons) List
Table 2014-2024 Mexico CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Mexico CIS Insulin Import & Export (Tons) List
Table 2014-2024 South America CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Figure 2014-2024 South America CIS Insulin Market Size (M USD) and CAGR
Figure 2014-2024 South America CIS Insulin Market Volume (Tons) and CAGR
Table 2014-2024 South America CIS Insulin Demand (Tons) List by Application
Table 2014-2019 South America CIS Insulin Key Players Sales (Tons) List
Table 2014-2019 South America CIS Insulin Key Players Market Share List
Table 2014-2024 South America CIS Insulin Demand (Tons) List by Type
Table 2014-2019 South America CIS Insulin Price (USD/Ton) List by Type
Table 2014-2024 Brazil CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Brazil CIS Insulin Import & Export (Tons) List
Table 2014-2024 Argentina CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Argentina CIS Insulin Import & Export (Tons) List
Table 2014-2024 Chile CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Chile CIS Insulin Import & Export (Tons) List
Table 2014-2024 Peru CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Peru CIS Insulin Import & Export (Tons) List
Table 2014-2024 Asia & Pacific CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Figure 2014-2024 Asia & Pacific CIS Insulin Market Size (M USD) and CAGR
Figure 2014-2024 Asia & Pacific CIS Insulin Market Volume (Tons) and CAGR
Table 2014-2024 Asia & Pacific CIS Insulin Demand (Tons) List by Application
Table 2014-2019 Asia & Pacific CIS Insulin Key Players Sales (Tons) List
Table 2014-2019 Asia & Pacific CIS Insulin Key Players Market Share List
Table 2014-2024 Asia & Pacific CIS Insulin Demand (Tons) List by Type
Table 2014-2019 Asia & Pacific CIS Insulin Price (USD/Ton) List by Type
Table 2014-2024 China CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 China CIS Insulin Import & Export (Tons) List
Table 2014-2024 India CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 India CIS Insulin Import & Export (Tons) List
Table 2014-2024 Japan CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Japan CIS Insulin Import & Export (Tons) List
Table 2014-2024 South Korea CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 South Korea CIS Insulin Import & Export (Tons) List
Table 2014-2024 ASEAN CIS Insulin Market Size (M USD) List
Table 2014-2024 ASEAN CIS Insulin Market Volume (Tons) List
Table 2014-2024 ASEAN CIS Insulin Import (Tons) List
Table 2014-2024 ASEAN CIS Insulin Export (Tons) List
Table 2014-2024 Australia CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Australia CIS Insulin Import & Export (Tons) List
Table 2014-2024 Europe CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Figure 2014-2024 Europe CIS Insulin Market Size (M USD) and CAGR
Figure 2014-2024 Europe CIS Insulin Market Volume (Tons) and CAGR
Table 2014-2024 Europe CIS Insulin Demand (Tons) List by Application
Table 2014-2019 Europe CIS Insulin Key Players Sales (Tons) List
Table 2014-2019 Europe CIS Insulin Key Players Market Share List
Table 2014-2024 Europe CIS Insulin Demand (Tons) List by Type
Table 2014-2019 Europe CIS Insulin Price (USD/Ton) List by Type
Table 2014-2024 Germany CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Germany CIS Insulin Import & Export (Tons) List
Table 2014-2024 France CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 France CIS Insulin Import & Export (Tons) List
Table 2014-2024 UK CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 UK CIS Insulin Import & Export (Tons) List
Table 2014-2024 Italy CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Italy CIS Insulin Import & Export (Tons) List
Table 2014-2024 Spain CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Spain CIS Insulin Import & Export (Tons) List
Table 2014-2024 Belgium CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Belgium CIS Insulin Import & Export (Tons) List
Table 2014-2024 Netherlands CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Netherlands CIS Insulin Import & Export (Tons) List
Table 2014-2024 Austria CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Austria CIS Insulin Import & Export (Tons) List
Table 2014-2024 Poland CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Poland CIS Insulin Import & Export (Tons) List
Table 2014-2024 Russia CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Russia CIS Insulin Import & Export (Tons) List
Table 2014-2024 MEA CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Figure 2014-2024 MEA CIS Insulin Market Size (M USD) and CAGR
Figure 2014-2024 MEA CIS Insulin Market Volume (Tons) and CAGR
Table 2014-2024 MEA CIS Insulin Demand (Tons) List by Application
Table 2014-2019 MEA CIS Insulin Key Players Sales (Tons) List
Table 2014-2019 MEA CIS Insulin Key Players Market Share List
Table 2014-2024 MEA CIS Insulin Demand (Tons) List by Type
Table 2014-2019 MEA CIS Insulin Price (USD/Ton) List by Type
Table 2014-2024 Egypt CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Egypt CIS Insulin Import & Export (Tons) List
Table 2014-2024 Iran CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Iran CIS Insulin Import & Export (Tons) List
Table 2014-2024 Israel CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Israel CIS Insulin Import & Export (Tons) List
Table 2014-2024 South Africa CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 South Africa CIS Insulin Import & Export (Tons) List
Table 2014-2024 GCC CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 GCC CIS Insulin Import & Export (Tons) List
Table 2014-2024 Turkey CIS Insulin Market Size (M USD) and Market Volume (Tons) List
Table 2014-2024 Turkey CIS Insulin Import & Export (Tons) List
Table 2014-2019 Global CIS Insulin Market Size (M USD) List by Region
Table 2014-2019 Global CIS Insulin Market Size Share List by Region
Table 2014-2019 Global CIS Insulin Market Volume (Tons) List by Region
Table 2014-2019 Global CIS Insulin Market Volume Share List by Region
Table 2014-2019 Global CIS Insulin Demand (Tons) List by Application
Table 2014-2019 Global CIS Insulin Demand Market Share List by Application
Table 2014-2019 Global CIS Insulin Capacity (Tons) List
Table 2014-2019 Global CIS Insulin Key Vendors Capacity Share List
Table 2014-2019 Global CIS Insulin Key Vendors Production (Tons) List
Table 2014-2019 Global CIS Insulin Key Vendors Production Share List
Figure 2014-2019 Global CIS Insulin Capacity Production and Growth Rate
Table 2014-2019 Global CIS Insulin Key Vendors Production Value (M USD) List
Figure 2014-2019 Global CIS Insulin Production Value (M USD) and Growth Rate
Table 2014-2019 Global CIS Insulin Key Vendors Production Value Share List
Table 2014-2019 Global CIS Insulin Demand (Tons) List by Type
Table 2014-2019 Global CIS Insulin Demand Market Share List by Type
Table 2014-2019 Regional CIS Insulin Price (USD/Ton) List
Table 2019-2024 Global CIS Insulin Market Size (M USD) List by Region
Table 2019-2024 Global CIS Insulin Market Size Share List by Region
Table 2019-2024 Global CIS Insulin Market Volume (Tons) List by Region
Table 2019-2024 Global CIS Insulin Market Volume Share List by Region
Table 2019-2024 Global CIS Insulin Demand (Tons) List by Application
Table 2019-2024 Global CIS Insulin Demand Market Share List by Application
Table 2019-2024 Global CIS Insulin Capacity (Tons) List
Table 2019-2024 Global CIS Insulin Key Vendors Capacity Share List
Table 2019-2024 Global CIS Insulin Key Vendors Production (Tons) List
Table 2019-2024 Global CIS Insulin Key Vendors Production Share List
Figure 2019-2024 Global CIS Insulin Capacity Production and Growth Rate
Table 2019-2024 Global CIS Insulin Key Vendors Production Value (M USD) List
Figure 2019-2024 Global CIS Insulin Production Value (M USD) and Growth Rate
Table 2019-2024 Global CIS Insulin Key Vendors Production Value Share List
Table 2019-2024 Global CIS Insulin Demand (Tons) List by Type
Table 2019-2024 Global CIS Insulin Demand Market Share List by Type
Table 2019-2024 Regional CIS Insulin Price (USD/Ton) List
Table Eli Lilly Information List
Table SWOT Analysis of Eli Lilly
Table 2014-2019 Eli Lilly CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Eli Lilly CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Eli Lilly CIS Insulin Market Share
Table Novo Nordisk Information List
Table SWOT Analysis of Novo Nordisk
Table 2014-2019 Novo Nordisk CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Novo Nordisk CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Novo Nordisk CIS Insulin Market Share
Table Takeda Pharmaceuticals Information List
Table SWOT Analysis of Takeda Pharmaceuticals
Table 2014-2019 Takeda Pharmaceuticals CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Takeda Pharmaceuticals CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Takeda Pharmaceuticals CIS Insulin Market Share
Table Sanofi Aventis Information List
Table SWOT Analysis of Sanofi Aventis
Table 2014-2019 Sanofi Aventis CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Sanofi Aventis CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Sanofi Aventis CIS Insulin Market Share
Table Nanjing Xinbai Pharmaceutical Information List
Table SWOT Analysis of Nanjing Xinbai Pharmaceutical
Table 2014-2019 Nanjing Xinbai Pharmaceutical CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Nanjing Xinbai Pharmaceutical CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Nanjing Xinbai Pharmaceutical CIS Insulin Market Share
Table Oramed Pharmaceuticals Information List
Table SWOT Analysis of Oramed Pharmaceuticals
Table 2014-2019 Oramed Pharmaceuticals CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Oramed Pharmaceuticals CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Oramed Pharmaceuticals CIS Insulin Market Share
Table Merck Information List
Table SWOT Analysis of Merck
Table 2014-2019 Merck CIS Insulin Product Capacity Production (Tons) Price Cost (USD/Ton) Production Value (M USD) List
Figure 2014-2019 Merck CIS Insulin Capacity Production (Tons) and Growth Rate
Figure 2014-2019 Merck CIS Insulin Market Share
......
......
Similar Reports
This report provides an overview of the French molecular diagnostic testing market, including test volume, and sales forecasts by Application, 2019-2023, and supplier shares by test.
Table of Contents
Business Environment
Market Structure
Market Size, Growth, and Major Suppliers' Market Shares
This report provides an overview of the German molecular diagnostic testing market, including test volume, and sales forecasts by application, and supplier shares by test.
Table of Contents
Business Environment
Market Structure
Market Size, Growth, and Major Suppliers' Market Shares
&nb...
- Publish Date: April 1, 2019
- $450
This report provides an overview of the Italian molecular diagnostic testing market, including test volume, and sales forecasts by application, and supplier shares by test.
Table of Contents
Business Environment
Market Structure
Market Size, Growth, and Major Suppliers' Market Shares
&nb...
- Publish Date: April 1, 2019
- $450
