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Pharmaceuticals

Global Aptamers Market

  • MAR2978834
  • 216 Pages
  • April 2018
  • Pharmaceuticals
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Earlier it was believed that the function of DNA was carrying genetic material and the function of RNA was to transfer it from gene to protein. However, other functions of Nucleic acids were later discovered. Aptamers are DNA or RNA based oligonucleotides. The term Aptamers come from the Latin word, aptus meaning to fit and meros meaning part. They are single-stranded molecules. They take a wide range of shapes and can easily bind with high selectivity and specificity.Some, of the common targets, are protein, peptides and carbohydrates.

End User/Technology

The most common forms of Aptamers areDNA, RNA and peptide aptamers.Aptamers discriminate between their targets with high precision and once selected, they bind to it with a strong bond. DNA and RNA aptamers are chosen from a wide range of nucleic acids and then optimized. This process is called SELEX.Once the target is found, the bonding happens by complementary RNA base-pairing.Secondary, structures like short helical arms and single-stranded loops are formed which combine the target to form tertiary structures and this bonding happens by van der Waals Forces hydrogen bonding and electrostatic interaction. DNA aptamers do not require reverse transcription, are stable and hence widely available compared to RNA aptamers.

Market Dynamics

Aptamers have a higher success rate of binding to large molecules as compared to antibodies, thanks to high investments in researchand development and latest technology. This has brought down costs and has led to the usage of aptamers in making new drugs and treatment of diseases. RNA aptamers have good diagnostic abilities and use in therapy. But, the aptamers are primarily sourced from animals. Stringent, regulations imposed by governments to reduce the use of animals for testing may prove to be a hindrance.Aptamers market is going to reach $8.91 billion in 2025 at a CAGR of 28.2%. Diseases like AIDS and Alzheimer's are driving the aptamers market

Market segmentation

Based on type:

--> Peptide

--> Nucleic Acid-based

Based on geography

--> Asia-Pacific

--> Europe

--> North America

--> Rest of The World

Based on industry

--> Diagnostics

--> Therapeutics

--> Research and Development

--> Others

Regional/Geographic Analysis

Aptamers market is going to reach $8.91 billion in 2025 at a CAGR of 28.2%.Globally, North America dominates the aptamers market because of favourable government policies and large investment in latest technology and R&D.In Europe, the aptamer technology is being used in small-scale industries and thus it had a market share of 35% globally which was second-largest after USGrowth, of aptamers in Asia-pacific is mainly due to diagnosis, therapy and manufacturing new drugs.The market was worth 24 million in 2016 and is predicted to become 66 million by 2021.

Key Players

--> AM Biotechnologies

--> Aptagen

--> Aptamer Sciences

--> BasePair Biotechnologies

--> Aptus Biotech

Report Contents:

> Market segments

> Market Drivers, Restraints and Opportunities

> Market Size & Forecast 2016 to 2022

> Supply & Demand Value Chain

> Market - Current Trends

> Competition & Major Companies

> Technology and R&D Status

> Porters Five Force Analysis

> Strategic and Critical Success Factor Analysis of Key Players

Regional Analysis:

> North America

>> US and Canada

> Latin America

>> Mexico, Brazil, Argentina and Rest of Latin America

> Western Europe

>> EU5 (Germany, France, Italy, Spain, U.K.)

>> Nordic Countries (Denmark, Finland, Norway, and Sweden)

>> Benelux (Belgium, The Netherlands, and Luxembourg)

>> Rest of Western Europe

> Eastern Europe

>> Russia

>> Poland

>> Rest of Eastern Europe

> Asia Pacific

>> China

>> India

>> Japan

>> Australia and New Zealand

>> Rest of Asia Pacific

> Middle East and Africa

>> GCC countries (Saudi Arabia, Oman, Qatar, Bahrain, UAE and Kuwait)

>> South Africa

>> North Africa

>> Rest of Middle East and Africa

This report is an elaborate aggregation of primary inputs from industry experts and participants across the supply chain. It provides details on market segmentation which is derived from several product mapping exercises, macroeconomic parameters and other qualitative and quantitative insights. The impact of all such factors is delivered across multiple market segments and geographies.

Report Highlights:

> Detailed Historical Overview (Market Origins, Product Launch Timeline, etc.)

> Consumer and Pricing Analysis

> Market dynamics of the industry

> Market Segmentation

> Estimated Market Sizing in terms of volume and value

> Recent trends in Market and impact

> Research Status and Technology Overview

> Extensive Industry Structure Coverage

 
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